On the role of the gap junction protein Cx43 (GJA1) in human cardiac malformations with Fallot-pathology. a study on paediatric cardiac specimen.

INTRODUCTION: Gap junction channels are involved in growth and differentiation. Therefore, we wanted to elucidate if the main cardiac gap junction protein connexin43 (GJA1) is altered in patients with Tetralogy of Fallot or double-outlet right ventricle of Fallot-type (62 patients referred to as Fal...

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Bibliographic Details
Main Authors: Aida Salameh, Josphina Haunschild, Paul Bräuchle, Oliver Peim, Thomas Seidel, Marko Reitmann, Martin Kostelka, Farhad Bakhtiary, Stefan Dhein, Ingo Dähnert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3994046?pdf=render