Biophysical Properties of Somatic and Axonal Voltage-Gated Sodium Channels in Midbrain Dopaminergic Neurons

Biophysical Properties of Somatic and Axonal Voltage-Gated Sodium Channels in Midbrain Dopaminergic Neurons

Spiking activities of midbrain dopaminergic neurons are critical for key brain functions including motor control and affective behaviors. Voltage-gated Na+ channels determine neuronal excitability and action potential (AP) generation. Previous studies on dopaminergic neuron excitability mainly focus...

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Bibliographic Details
Main Authors: Jun Yang, Yujie Xiao, Liang Li, Quansheng He, Min Li, Yousheng Shu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
voltage-gated sodium (Nav) channels
action potential
sodium channel subtype
axon
dopaminergic neuron
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00317/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00317/full

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