A biomaterials approach to influence stem cell fate in injectable cell-based therapies

Abstract Background Numerous stem cell therapies use injection-based administration to deliver high-density cell preparations. However, cell retention rates as low as 1% have been observed within days of transplantation. This study investigated the effects of varying administration and formulation p...

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Bibliographic Details
Main Authors: Mahetab H. Amer, Felicity R. A. J. Rose, Kevin M. Shakesheff, Lisa J. White
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-018-0789-1