AMPA receptors commandeer an ancient cargo exporter for use as an auxiliary subunit for signaling.

Fast excitatory neurotransmission in the mammalian central nervous system is mainly mediated by ionotropic glutamate receptors of the AMPA subtype (AMPARs). AMPARs are protein complexes of the pore-lining α-subunits GluA1-4 and auxiliary β-subunits modulating their trafficking and gating. By a prote...

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Bibliographic Details
Main Authors: Nadine Harmel, Barbara Cokic, Gerd Zolles, Henrike Berkefeld, Veronika Mauric, Bernd Fakler, Valentin Stein, Nikolaj Klöcker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22292017/pdf/?tool=EBI