Formulation and evalution of montelukast sodium - chitosan based spray dried microspheres for pulmonary drug delivery

Formulation and evalution of montelukast sodium - chitosan based spray dried microspheres for pulmonary drug delivery

The objective of present work was to prepare microspheres of montelukast sodium using a natural polymer- chitosan by spray drying method by using glutaraldehyde as a cross linking agent. The microspheres were characterized for size, shape, dissolution, swelling and mucoadhesion. It was observed that...

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Bibliographic Details
Main Authors: Rushi Panchal, Harsha Patel, Vishnu Patel, Pratik Joshi, Ankit Parikh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Pharmacy and Bioallied Sciences
Subjects:
Chitosan
gluteraldehyde
microspheres
montelukast sodium
mucosdhesion
spray dryer
Online Access:http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=5;spage=110;epage=111;aulast=Panchal

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http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=5;spage=110;epage=111;aulast=Panchal

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