EspF is crucial for Citrobacter rodentium-induced tight junction disruption and lethality in immunocompromised animals.

Attaching/Effacing (A/E) bacteria include human pathogens enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E. coli (EHEC), and their murine equivalent Citrobacter rodentium (CR), of which EPEC and EHEC are important causative agents of foodborne diseases worldwide. While A/E pathogen infe...

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Bibliographic Details
Main Authors: Xue Xia, Yue Liu, Andrea Hodgson, Dongqing Xu, Wenxuan Guo, Hongbing Yu, Weifeng She, Chenxing Zhou, Lei Lan, Kai Fu, Bruce A Vallance, Fengyi Wan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007898