Biliary lipid secretion: immunolocalization and identification of a protein associated with lamellar cholesterol carriers in supersaturated rat and human bile.

Feeding a 0.5% diosgenin plus 0.02% simvastatin diet to rats increases biliary cholesterol concentration and saturation to levels generally found in human native supersaturated bile. By using preparative ultracentrifugation, gel filtration chromatography, and electron microscopy, we isolated, purifi...

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Bibliographic Details
Main Authors: A Rigotti, L Núñez, L Amigo, L Puglielli, J Garrido, M Santos, S González, G Mingrone, A Greco, F Nervi
Format: Article
Language:English
Published: Elsevier 1993-11-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520351063