Dazl is a target RNA suppressed by mammalian NANOS2 in sexually differentiating male germ cells

The Nanos family protein, NANOS2, is required for sexual differentiation of male germ cells in mice, however, the molecular RNA targets are unknown. Here, Kato et al. identify Dazl, a germ cell-specific gene, as being a target of NANOS, with stabilized DazlmRNA causing abnormal resumption of the cel...

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Bibliographic Details
Main Authors: Yuzuru Kato, Takeo Katsuki, Hiroki Kokubo, Aki Masuda, Yumiko Saga
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11272