SiNPle: Fast and Sensitive Variant Calling for Deep Sequencing Data

Current high-throughput sequencing technologies can generate sequence data and provide information on the genetic composition of samples at very high coverage. Deep sequencing approaches enable the detection of rare variants in heterogeneous samples, such as viral quasi-species, but also have the un...

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Bibliographic Details
Main Authors: Luca Ferretti, Chandana Tennakoon, Adrian Silesian, Graham Freimanis, Paolo Ribeca
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/10/8/561