Immunomodulation of Host Chitinase 3-Like 1 During a Mammary Pathogenic Escherichia coli Infection

Chitin is a N-acetyl-d-glucosamine biopolymer that can be recognized by chitin-binding proteins. Although mammals lack chitin synthase, they induce proteins responsible for detecting chitin in response to bacterial infections. Our aim was to investigate whether chitinase 3-like 1 (CHI3L1) has a pote...

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Bibliographic Details
Main Authors: Koen Breyne, Jonas Steenbrugge, Kristel Demeyere, Chun Geun Lee, Jack A. Elias, Wolfram Petzl, David G. E. Smith, Pierre Germon, Evelyne Meyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01143/full