Melatonin: From Pharmacokinetics to Clinical Use in Autism Spectrum Disorder

Melatonin: From Pharmacokinetics to Clinical Use in Autism Spectrum Disorder

The role of melatonin has been extensively investigated in pathophysiological conditions, including autism spectrum disorder (ASD). Reduced melatonin secretion has been reported in ASD and led to many clinical trials using immediate-release and prolonged-release oral formulations of melatonin. Howev...

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Bibliographic Details
Main Authors: Sébastien Lalanne, Claire Fougerou-Leurent, George M. Anderson, Carmen M. Schroder, Tali Nir, Sylvie Chokron, Richard Delorme, Bruno Claustrat, Eric Bellissant, Solenn Kermarrec, Patricia Franco, Laure Denis, Sylvie Tordjman
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
melatonin
circadian rhythm
pharmacokinetics
autism
autism spectrum disorder (ASD), autistic behavioral impairments
concentration-effect relationship
Online Access:https://www.mdpi.com/1422-0067/22/3/1490

Internet

https://www.mdpi.com/1422-0067/22/3/1490

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