A novel allele in the promoter of the hepatic lipase is associated with increased concentration of HDL-C and decreased promoter activity

Hepatic lipase (HL) is a lipolytic enzyme involved in the metabolism of plasma lipoproteins, especially HDLs. Association of the polymorphisms in the promoter region of the LIPC gene to post-heparin plasma HL activity and the plasma HDL-C concentration has been investigated thoroughly, but to date l...

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Bibliographic Details
Main Authors: Zhiguang Su, Sizhong Zhang, Daniel W. Nebert, Li Zhang, Dejia Huang, Yiping Hou, Linchuan Liao, Cuiying Xiao
Format: Article
Language:English
Published: Elsevier 2002-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520327784