Chromosome End Repair and Genome Stability in Plasmodium falciparum

The human malaria parasite Plasmodium falciparum replicates within circulating red blood cells, where it is subjected to conditions that frequently cause DNA damage. The repair of DNA double-stranded breaks (DSBs) is thought to rely almost exclusively on homologous recombination (HR), due to a lack...

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Bibliographic Details
Main Authors: Susannah F. Calhoun, Jake Reed, Noah Alexander, Christopher E. Mason, Kirk W. Deitsch, Laura A. Kirkman, Jon P. Boyle
Format: Article
Language:English
Published: American Society for Microbiology 2017-08-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/4/e00547-17