Fine mapping of the NRG1 Hirschsprung's disease locus.

Fine mapping of the NRG1 Hirschsprung's disease locus.

The primary pathology of Hirschsprung's disease (HSCR, colon aganglionosis) is the absence of ganglia in variable lengths of the hindgut, resulting in functional obstruction. HSCR is attributed to a failure of migration of the enteric ganglion precursors along the developing gut. RET is a key r...

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Bibliographic Details
Main Authors: Clara Sze-Man Tang, Wai-Kiu Tang, Man-Ting So, Xiao-Ping Miao, Brian Man-Chun Leung, Benjamin Hon-Kei Yip, Thomas Yuk-Yu Leon, Elly Sau-Wai Ngan, Vincent Chi-Hang Lui, Yan Chen, Ivy Hau-Yee Chan, Patrick Ho-Yu Chung, Xue-Lai Liu, Xuan-Zhao Wu, Kenneth Kak-Yuen Wong, Pak-Chung Sham, Stacey S Cherny, Paul Kwong-Hang Tam, Maria-Mercè Garcia-Barceló
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3024406?pdf=render

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http://europepmc.org/articles/PMC3024406?pdf=render

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