Structural and biochemical studies on ATP binding and hydrolysis by the Escherichia coli RNA chaperone Hfq.

In Escherichia coli the RNA chaperone Hfq is involved in riboregulation by assisting base-pairing between small regulatory RNAs (sRNAs) and mRNA targets. Several structural and biochemical studies revealed RNA binding sites on either surface of the donut shaped Hfq-hexamer. Whereas sRNAs are believe...

Full description

Bibliographic Details
Main Authors: Hermann Hämmerle, Mads Beich-Frandsen, Branislav Večerek, Lukas Rajkowitsch, Oliviero Carugo, Kristina Djinović-Carugo, Udo Bläsi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23226421/pdf/?tool=EBI