Iduronic acid in chondroitin/dermatan sulfate affects directional migration of aortic smooth muscle cells.
Aortic smooth muscle cells produce chondroitin/dermatan sulfate (CS/DS) proteoglycans that regulate extracellular matrix organization and cell behavior in normal and pathological conditions. A unique feature of CS/DS proteoglycans is the presence of iduronic acid (IdoA), catalyzed by two DS epimeras...
Main Authors: | Barbara Bartolini, Martin A Thelin, Lena Svensson, Giancarlo Ghiselli, Toin H van Kuppevelt, Anders Malmström, Marco Maccarana |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3699603?pdf=render |
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