Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest

Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest

Many environmental and physiological stresses are chronic. Thus, cells are constantly exposed to diverse types of genotoxic insults that challenge genome stability, including those that induce oxidative DNA damage. However, most in vitro studies that model cellular response to oxidative stressors em...

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Bibliographic Details
Main Authors: Gloria A. Santa-Gonzalez, Andrea Gomez-Molina, Mauricio Arcos-Burgos, Joel N. Meyer, Mauricio Camargo
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Redox Biology
Subjects:
ROS
Genotoxicity
DNA damage response
Up-regulation of DNA repair genes
G2/M arrest
Adaptation
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716300751

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http://www.sciencedirect.com/science/article/pii/S2213231716300751

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