Clinical effects of ursodeoxycholic acid on patients with ulcerative colitis may improve via the regulation of IL-23-IL-17 axis and the changes of the proportion of intestinal microflora

Clinical effects of ursodeoxycholic acid on patients with ulcerative colitis may improve via the regulation of IL-23-IL-17 axis and the changes of the proportion of intestinal microflora

Background: We aimed to evaluate the therapeutic effect of additional ursodeoxycholic acid (UDCA) with mesalazine, compared to mesalazine alone in patients with ulcerative colitis (UC). The mechanism was evaluated by monitoring the changes of IL-23-IL-17 axis and the intestinal microflora. Methods:...

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Bibliographic Details
Main Authors: Zhengjun Wang, Jinhua Chen, Zhiping Chen, Longke Xie, Wen Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:The Saudi Journal of Gastroenterology
Subjects:
il-23
il-17
mesalazine
microflora
ulcerative colitis
ursodeoxycholic acid
Online Access:http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2021;volume=27;issue=3;spage=149;epage=157;aulast=Wang

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http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2021;volume=27;issue=3;spage=149;epage=157;aulast=Wang

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