Differentiated neuroprogenitor cells incubated with human or canine adenovirus, or lentiviral vectors have distinct transcriptome profiles.

Differentiated neuroprogenitor cells incubated with human or canine adenovirus, or lentiviral vectors have distinct transcriptome profiles.

Several studies have demonstrated the potential for vector-mediated gene transfer to the brain. Helper-dependent (HD) human (HAd) and canine (CAV-2) adenovirus, and VSV-G-pseudotyped self-inactivating HIV-1 vectors (LV) effectively transduce human brain cells and their toxicity has been partly analy...

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Bibliographic Details
Main Authors: Stefania Piersanti, Letizia Astrologo, Valerio Licursi, Rossella Costa, Enrica Roncaglia, Aurelie Gennetier, Sandy Ibanes, Miguel Chillon, Rodolfo Negri, Enrico Tagliafico, Eric J Kremer, Isabella Saggio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724896?pdf=render

Internet

http://europepmc.org/articles/PMC3724896?pdf=render

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