LC-MS/MS Method for Rapid Quantification of Progesterone in Rabbit Plasma and Its Application in a Pharmacokinetic Study of the Transdermal Formulation

A rapid and effective method using QuEChERS-based sample preparation procedure and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis has been developed and validated to determine progesterone in rabbit plasma. The analyte was extracted from plasma by acetonitrile with phase partitio...

Full description

Bibliographic Details
Main Authors: Cao-Son Tran, Quang-Dong Bui, Ngoc-Tho Thi Nguyen, Minh-Hanh Dao, Thach-Tung Nguyen
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2020/8889375