Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth.

The persistence of a reservoir of latently infected CD4 T cells remains one of the major obstacles to cure HIV. Numerous strategies are being explored to eliminate this reservoir. To translate these efforts into clinical trials, there is a strong need for validated biomarkers that can monitor the re...

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Bibliographic Details
Main Authors: Maja Kiselinova, Ward De Spiegelaere, Maria Jose Buzon, Eva Malatinkova, Mathias Lichterfeld, Linos Vandekerckhove
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4777389?pdf=render