Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.

Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.

<h4>Background</h4>Raised C-reactive protein (CRP) is a risk factor for type 2 diabetes. According to the Mendelian randomization method, the association is likely to be causal if genetic variants that affect CRP level are associated with markers of diabetes development and diabetes. Our...

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Bibliographic Details
Main Authors: Eric J Brunner, Mika Kivimäki, Daniel R Witte, Debbie A Lawlor, George Davey Smith, Jackie A Cooper, Michelle Miller, Gordon D O Lowe, Ann Rumley, Juan P Casas, Tina Shah, Steve E Humphries, Aroon D Hingorani, Michael G Marmot, Nicholas J Timpson, Meena Kumari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Medicine
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18700811/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18700811/pdf/?tool=EBI

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