Preosteocytes/osteocytes have the potential to dedifferentiate becoming a source of osteoblasts.

Presently there is no clear evidence for the ability of mature osteogenic lineage cells to dedifferentiate. In order to identify and trace mature osteogenic lineage cells, we have utilized transgenic mouse models in which the dentin matrix protein 1 (Dmp1) promoter drives expression of GFP (active m...

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Bibliographic Details
Main Authors: Elena Torreggiani, Brya G Matthews, Slavica Pejda, Igor Matic, Mark C Horowitz, Danka Grcevic, Ivo Kalajzic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3765403?pdf=render