PPAR Gamma-Regulated MicroRNA 199a-5p Underlies Bone Marrow Adiposity in Aplastic Anemia

PPAR Gamma-Regulated MicroRNA 199a-5p Underlies Bone Marrow Adiposity in Aplastic Anemia

Increased propensity of bone marrow-derived mesenchymal stem cells (BM-MSCs) toward adipogenic differentiation has been implicated in the fatty bone marrow and defective hematopoiesis of aplastic anemia (AA). However, the underlying molecular mechanism remains to be investigated. In this study, we f...

Full description

Bibliographic Details
Main Authors: Xianning Zhang, Lulu Liu, Cuiyun Dou, Panpan Cheng, Lei Liu, Haihui Liu, Saisai Ren, Cuiling Wang, Shu Jia, Lulu Chen, Hao Zhang, Mingtai Chen
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253119301957

Internet

http://www.sciencedirect.com/science/article/pii/S2162253119301957

Similar Items