Cardiomyocyte-specific miRNA-30c over-expression causes dilated cardiomyopathy.

MicroRNAs (miRNAs) regulate many aspects of cellular function and their deregulation has been implicated in heart disease. MiRNA-30c is differentially expressed in the heart during the progression towards heart failure and in vitro studies hint to its importance in cellular physiology. As little is...

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Main Authors: Wino J Wijnen, Ingeborg van der Made, Stephanie van den Oever, Monika Hiller, Bouke A de Boer, Daisy I Picavet, Iliana A Chatzispyrou, Riekelt H Houtkooper, Anke J Tijsen, Jaco Hagoort, Henk van Veen, Vincent Everts, Jan M Ruijter, Yigal M Pinto, Esther E Creemers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4008570?pdf=render