Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition.

Targeting melanoma metastasis and immunosuppression with a new mode of melanoma inhibitory activity (MIA) protein inhibition.

Melanoma is the most aggressive form of skin cancer, with fast progression and early dissemination mediated by the melanoma inhibitory activity (MIA) protein. Here, we discovered that dimerization of MIA is required for functional activity through mutagenesis of MIA which showed the correlation betw...

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Bibliographic Details
Main Authors: Jennifer Schmidt, Alexander Riechers, Raphael Stoll, Thomas Amann, Florian Fink, Thilo Spruss, Wolfram Gronwald, Burkhard König, Claus Hellerbrand, Anja Katrin Bosserhoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22666418/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22666418/?tool=EBI

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