The lncRNA XIST/miR‐125b‐2‐3p axis modulates cell proliferation and chemotherapeutic sensitivity via targeting Wee1 in colorectal cancer

The lncRNA XIST/miR‐125b‐2‐3p axis modulates cell proliferation and chemotherapeutic sensitivity via targeting Wee1 in colorectal cancer

Abstract Background Numerous reports on microRNAs have illustrated their role in tumor growth and metastasis. Recently, a new prognostic factor, miR‐125b‐2‐3p, has been identified for predicting chemotherapeutic sensitivity in advanced colorectal cancer (CRC). However, the specific mechanisms and bi...

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Bibliographic Details
Main Authors: Zhao‐lei Zeng, Jia‐huan Lu, Yun Wang, Hui Sheng, Ying‐nan Wang, Zhan‐hong Chen, Qi‐nian Wu, Jia‐Bo Zheng, Yan‐xing Chen, Dong‐dong Yang, Kai Yu, Hai‐yu Mo, Jia‐jia Hu, Pei‐shan Hu, Ze‐xian Liu, Huai‐qiang Ju, Rui‐Hua Xu
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Cancer Medicine
Subjects:
chemotherapeutic sensitivity
colorectal cancer
drug resistance
miR‐125b‐2‐3p
Online Access:https://doi.org/10.1002/cam4.3777

Internet

https://doi.org/10.1002/cam4.3777

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