Highly sensitive diagnostic method for colorectal cancer using the ratio of free DNA fragments in serum

Highly sensitive diagnostic method for colorectal cancer using the ratio of free DNA fragments in serum

Objectives: The correlations of the ratio of long-/short-chain DNA fragments in blood with the existence of cancer and the clinicopathological features of colorectal cancer (CRC) were examined. The potential use of this ratio for diagnostic screening was evaluated. Methods: DNA concentrations were a...

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Bibliographic Details
Main Authors: Satoshi Arakawa, Soji Ozawa, Takashi Ando, Hiroya Takeuchi, Yuko Kitagawa, Jin Kawase, Hisanori Oshima, Hidetoshi Nagata, Koji Atsuta, Rie Yoshida, Norihiko Kawabe, Shunji Umemoto, Zenichi Morise, Akihiko Horiguchi
Format: Article
Language:English
Published: Fujita Medical Society 2019-02-01
Series:Fujita Medical Journal
Subjects:
colorectal cancer
dna fragments
alu247/115 ratio
real-time polymerase chain reaction
Online Access:https://www.jstage.jst.go.jp/article/fmj/5/1/5_2017-025/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/fmj/5/1/5_2017-025/_pdf/-char/en

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