MHC mismatch inhibits neurogenesis and neuron maturation in stem cell allografts.

The role of histocompatibility and immune recognition in stem cell transplant therapy has been controversial, with many reports arguing that undifferentiated stem cells are protected from immune recognition due to the absence of major histocompatibility complex (MHC) markers. This argument is even m...

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Bibliographic Details
Main Authors: Zhiguo Chen, Lori K Phillips, Elizabeth Gould, Jay Campisi, Star W Lee, Brandi K Ormerod, Monika Zwierzchoniewska, Olivia M Martinez, Theo D Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3068158?pdf=render