Use of a Guinea pig-specific transcriptome array for evaluation of protective immunity against genital chlamydial infection following intranasal vaccination in Guinea pigs.

Use of a Guinea pig-specific transcriptome array for evaluation of protective immunity against genital chlamydial infection following intranasal vaccination in Guinea pigs.

Guinea pigs have been used as a second animal model to validate putative anti-chlamydial vaccine candidates tested in mice. However, the lack of guinea pig-specific reagents has limited the utility of this animal model in Chlamydia sp. vaccine studies. Using a novel guinea pig-specific transcriptome...

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Bibliographic Details
Main Authors: Shradha Wali, Rishein Gupta, Ronald L Veselenak, Yansong Li, Jieh-Juen Yu, Ashlesh K Murthy, Andrew P Cap, M Neal Guentzel, James P Chambers, Guangming Zhong, Roger G Rank, Richard B Pyles, Bernard P Arulanandam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4263467?pdf=render

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http://europepmc.org/articles/PMC4263467?pdf=render

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