Endotoxin Exposure during Sensitization to Blomia tropicalis Allergens Shifts TH2 Immunity Towards a TH17-Mediated Airway Neutrophilic Inflammation: Role of TLR4 and TLR2.

Endotoxin Exposure during Sensitization to Blomia tropicalis Allergens Shifts TH2 Immunity Towards a TH17-Mediated Airway Neutrophilic Inflammation: Role of TLR4 and TLR2.

Experimental evidence and epidemiological studies indicate that exposure to endotoxin lipopolysaccharide (eLPS) or other TLR agonists prevent asthma. We have previously shown in the OVA-model of asthma that eLPS administration during alum-based allergen sensitization blocked the development of lung...

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Bibliographic Details
Main Authors: Renato Barboza, Niels Olsen Saraiva Câmara, Eliane Gomes, Anderson Sá-Nunes, Esther Florsheim, Luciana Mirotti, Alexis Labrada, Neuza Maria Alcântara-Neves, Momtchilo Russo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3689683?pdf=render

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http://europepmc.org/articles/PMC3689683?pdf=render

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