Prothrombotic Effect of Anti-beta-2 Glycoprotein-1 Antibodies on the Expression of Tissue Factor, Thrombomodulin, and Plasminogen Activator Inhibitor-1 in Endothelial Cells

Aim: to analyse the effects of immunoglobulin (Ig)G and IgM anti-beta-2 glycoprotein-1 (anti-β2GP1) on the expression of tissue factor (TF), thrombomodulin (TM), and plasminogen activator inhibitor-1(PAI-1) of endothelial cells in the messenger RNA level. Methods: laboratory experimental study in hu...

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Bibliographic Details
Main Authors: Rikarni Rikarni, Rahajuningsih Dharma, Tambunan L Tambunan, Harry Isbagyo, Beti E. E Dewi, Nuzirwan Acang, Rianto Setiabudy, Adi K Aman
Format: Article
Language:English
Published: Interna Publishing 2015-03-01
Series:Acta Medica Indonesiana
Online Access:http://www.actamedindones.org/index.php/ijim/article/view/6