Tag SNP polymorphism of CCL2 and its role in clinical tuberculosis in Han Chinese pediatric population.

BACKGROUND: Chemokine (C-C motif) ligand 2 CCL2/MCP-1 is among the key signaling molecules of innate immunity; in particular, it is involved in recruitment of mononuclear and other cells in response to infection, including tuberculosis (TB) and is essential for granuloma formation. METHODOLOGY/PRINC...

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Main Authors: Wei-Xing Feng, Igor Mokrousov, Bin-Bin Wang, Hugh Nelson, Wei-Wei Jiao, Jing Wang, Lin Sun, Si-Rui Zhou, Jing Xiao, Yi Gu, Xi-Rong Wu, Xu Ma, Adong Shen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084193?pdf=render