Evidence of early microstructural white matter abnormalities in multiple sclerosis from multi-shell diffusion MRI

Evidence of early microstructural white matter abnormalities in multiple sclerosis from multi-shell diffusion MRI

Irreversible white matter (WM) damage, including severe demyelination and axonal loss, is a main determinant of long-term disability in multiple sclerosis (MS). Non-invasive detection of changes in microstructural WM integrity in the disease is challenging since commonly used imaging metrics lack th...

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Bibliographic Details
Main Authors: Silvia De Santis, Tobias Granberg, Russell Ouellette, Constantina A. Treaba, Elena Herranz, Qiuyun Fan, Caterina Mainero, Nicola Toschi
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S221315821930049X

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http://www.sciencedirect.com/science/article/pii/S221315821930049X

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