A structural keystone for drug design

3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether biologically active compounds are known. Both tasks require more information than the structures themselves provide. For t...

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Bibliographic Details
Main Authors: Rother Kristian, Dunkel Mathias, Michalsky Elke, Trissl Silke, Goede Andrean, Leser Ulf, Preissner Robert
Format: Article
Language:English
Published: De Gruyter 2006-06-01
Series:Journal of Integrative Bioinformatics
Online Access:https://doi.org/10.2390/biecoll-jib-2006-19