POSH Localizes Activated Rac1 to Control the Formation of Cytoplasmic Dilation of the Leading Process and Neuronal Migration

The formation of proximal cytoplasmic dilation in the leading process (PCDLP) of migratory neocortical neurons is crucial for somal translocation and neuronal migration, processes that require the elaborate coordination of F-actin dynamics, centrosomal movement, and nucleokinesis. However, the unde...

Full description

Bibliographic Details
Main Authors: Tao Yang, Yiming Sun, Feng Zhang, Yuangang Zhu, Lei Shi, Huashun Li, Zhiheng Xu
Format: Article
Language:English
Published: Elsevier 2012-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471200232X