The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures

The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures

Two-component systems (TCSs) consist of a histidine kinase and a response regulator. Here, we evaluated the conservation of the AgrAC TCS among 149 completely sequenced Staphylococcus aureus strains. It is composed of four genes: agrBDCA. We found that: (i) AgrAC system (agr) was found in all but on...

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Bibliographic Details
Main Authors: Kumari S. Choudhary, Nathan Mih, Jonathan Monk, Erol Kavvas, James T. Yurkovich, George Sakoulas, Bernhard O. Palsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Microbiology
Subjects:
Staphylococcus
AgrAC
agr types
genomic arrangements
virulence
bioinformatics
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01082/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01082/full

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