Quantitative analysis of signaling responses during mouse primordial germ cell specification

During early mammalian development, the pluripotent cells of the embryo are exposed to a combination of signals that drive exit from pluripotency and germ layer differentiation. At the same time, a small population of pluripotent cells give rise to the primordial germ cells (PGCs), the precursors of...

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Bibliographic Details
Main Authors: Sophie M. Morgani, Anna-Katerina Hadjantonakis
Format: Article
Language:English
Published: The Company of Biologists 2021-05-01
Series:Biology Open
Subjects:
bmp
wnt
Online Access:http://bio.biologists.org/content/10/5/bio058741