Clozapine-treated Patients Have Marked Gastrointestinal Hypomotility, the Probable Basis of Life-threatening Gastrointestinal Complications: A Cross Sectional Study

Clozapine-treated Patients Have Marked Gastrointestinal Hypomotility, the Probable Basis of Life-threatening Gastrointestinal Complications: A Cross Sectional Study

Background: Gastrointestinal side effects are particularly common with clozapine and occur with other antipsychotics, ranging from mild constipation to fatal bowel obstruction and/or ischemia. While this adverse-effect spectrum has been attributed to ‘gastrointestinal hypomotility’, gastrointestinal...

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Bibliographic Details
Main Authors: Susanna Every-Palmer, Mike Nowitz, James Stanley, Eve Grant, Mark Huthwaite, Helen Dunn, Pete M. Ellis
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:EBioMedicine
Subjects:
Antipsychotic agents
Clozapine
Gastrointestinal tract
Laxatives
Constipation
Gastrointestinal motility
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416300536

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http://www.sciencedirect.com/science/article/pii/S2352396416300536

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