Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury

Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury

Abstract Background Vascular endothelial cadherin (VE-cadherin) is a membrane protein that is the major component of adherens junctions between endothelial cells. It is crucial for regulating vascular integrity, endothelial permeability, and angiogenesis. During inflammatory processes, VE-cadherin i...

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Bibliographic Details
Main Authors: Wen-Kuang Yu, J. Brennan McNeil, Nancy E. Wickersham, Ciara M. Shaver, Julie A. Bastarache, Lorraine B. Ware
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Critical Care
Subjects:
Endothelial injury
Sepsis
Soluble vascular endothelial cadherin
Acute kidney injury
Renal replacement therapy
Online Access:http://link.springer.com/article/10.1186/s13054-019-2315-y

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http://link.springer.com/article/10.1186/s13054-019-2315-y

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