Current Understanding on the Role of Standard and Immunoproteasomes in Inflammatory/Immunological Pathways of Multiple Sclerosis

The ubiquitin-proteasome system is the major intracellular molecular machinery for protein degradation and maintenance of protein homeostasis in most human cells. As ubiquitin-proteasome system plays a critical role in the regulation of the immune system, it might also influence the development and...

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Bibliographic Details
Main Authors: Elena Bellavista, Aurelia Santoro, Daniela Galimberti, Cristoforo Comi, Fabio Luciani, Michele Mishto
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Autoimmune Diseases
Online Access:http://dx.doi.org/10.1155/2014/739705