Repeated Administrations of Human Umbilical Cord Blood Cells Improve Disease Outcomes in a Mouse Model of Sanfilippo Syndrome Type III B

Repeated Administrations of Human Umbilical Cord Blood Cells Improve Disease Outcomes in a Mouse Model of Sanfilippo Syndrome Type III B

Sanfilippo syndrome type III B (MPS III B) is an inherited disorder characterized by a deficiency of α- N -acetylglucosaminidase (Naglu) enzyme leading to accumulation of heparan sulfate in lysosomes and severe neurological deficits. We have previously shown that a single administration of human umb...

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Bibliographic Details
Main Authors: Alison E. Willing Ph.D., Svitlana N. Garbuzova-Davis, Olga Zayko, Hiranya M. Derasari, Ashley E. Rawls, Chris R. James, Ron F. Mervis, Cyndy D. Sanberg, Nicole Kuzmin-Nichols, Paul R. Sanberg
Format: Article
Language:English
Published: SAGE Publishing 2014-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368914X676916

Internet

https://doi.org/10.3727/096368914X676916

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