Repeated Administrations of Human Umbilical Cord Blood Cells Improve Disease Outcomes in a Mouse Model of Sanfilippo Syndrome Type III B
Sanfilippo syndrome type III B (MPS III B) is an inherited disorder characterized by a deficiency of α- N -acetylglucosaminidase (Naglu) enzyme leading to accumulation of heparan sulfate in lysosomes and severe neurological deficits. We have previously shown that a single administration of human umb...
Main Authors: | Alison E. Willing Ph.D., Svitlana N. Garbuzova-Davis, Olga Zayko, Hiranya M. Derasari, Ashley E. Rawls, Chris R. James, Ron F. Mervis, Cyndy D. Sanberg, Nicole Kuzmin-Nichols, Paul R. Sanberg |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2014-12-01
|
Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368914X676916 |
Similar Items
-
Human umbilical cord blood treatment in a mouse model of ALS: optimization of cell dose.
by: Svitlana Garbuzova-Davis, et al.
Published: (2008-06-01) -
The Treatment of Neurodegenerative Disorders Using Umbilical Cord Blood and Menstrual Blood-Derived Stem Cells
by: Paul R. Sanberg, et al.
Published: (2011-02-01) -
Blood-brain barrier impairment in an animal model of MPS III B.
by: Svitlana Garbuzova-Davis, et al.
Published: (2011-01-01) -
Biodistribution of Infused Human Umbilical Cord Blood Cells in Alzheimer's Disease-Like Murine Model
by: Jared Ehrhart Ph.D., et al.
Published: (2016-01-01) -
Multiple intravenous administrations of human umbilical cord blood cells benefit in a mouse model of ALS.
by: Svitlana Garbuzova-Davis, et al.
Published: (2012-01-01)