Tumor-Secreted Exosomal lncRNA POU3F3 Promotes Cisplatin Resistance in ESCC by Inducing Fibroblast Differentiation into CAFs

Cancer-associated fibroblasts (CAFs), an activated subpopulation of fibroblasts, occupy a central position in the tumor microenvironment and have been shown to promote chemoresistance in multiple cancer types by secreting inflammatory cytokines. Herein, we report that tumor-secreted exosomal long no...

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Bibliographic Details
Main Authors: Yusuo Tong, Lili Yang, Changhua Yu, Weiguo Zhu, Xilei Zhou, Yaozu Xiong, Wanwei Wang, Fuzhi Ji, Dongcheng He, Xiufeng Cao
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520300772