Epithelial Na+ Channel: Reciprocal Control by COMMD10 and Nedd4-2

Optimal function of the epithelial sodium channel (ENaC) in the distal nephron is key to the kidney’s long-term control of salt homeostasis and blood pressure. Multiple pathways alter ENaC cell surface populations, including correct processing and trafficking in the secretory pathway to the cell sur...

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Bibliographic Details
Main Authors: Adam W. Ware, Tanya T. Cheung, Sahib Rasulov, Ezra Burstein, Fiona J. McDonald
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00793/full