Genome-wide analysis reveals novel genes essential for heme homeostasis in Caenorhabditis elegans.
Heme is a cofactor in proteins that function in almost all sub-cellular compartments and in many diverse biological processes. Heme is produced by a conserved biosynthetic pathway that is highly regulated to prevent the accumulation of heme--a cytotoxic, hydrophobic tetrapyrrole. Caenorhabditis eleg...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-07-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2912396?pdf=render |