Cerebrospinal Fluid Neurofilament Light Chain Is Associated with Kynurenine Pathway Metabolite Changes in Multiple Sclerosis

Neurofilament light (NFL) has proved to be a good prognostic factor in multiple sclerosis (MS), as its level is proportionally elevated with extended neuraxonal damage. The involvement of the kynurenine pathway in neuroinflammation has been proved. The precursor of this pathway is the essential amin...

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Bibliographic Details
Main Authors: Cecilia Rajda, Zsolt Galla, Helga Polyák, Zoltán Maróti, Kristóf Babarczy, Dániel Pukoli, László Vécsei
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
CSF
Online Access:https://www.mdpi.com/1422-0067/21/8/2665