Optimization of Sample Preparation for Metabolomics Exploration of Urine, Feces, Blood and Saliva in Humans Using Combined NMR and UHPLC-HRMS Platforms

Optimization of Sample Preparation for Metabolomics Exploration of Urine, Feces, Blood and Saliva in Humans Using Combined NMR and UHPLC-HRMS Platforms

Currently, most clinical studies in metabolomics only consider a single type of sample such as urine, plasma, or feces and use a single analytical platform, either NMR or MS. Although some studies have already investigated metabolomics data from multiple fluids, the information is limited to a uniqu...

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Bibliographic Details
Main Authors: Cécile Martias, Nadine Baroukh, Sylvie Mavel, Hélène Blasco, Antoine Lefèvre, Léa Roch, Frédéric Montigny, Julie Gatien, Laurent Schibler, Diane Dufour-Rainfray, Lydie Nadal-Desbarats, Patrick Emond
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
biological fluids
extraction protocol
UHPLC-HRMS
<sup>1</sup>H-NMR
metabolomic card
Online Access:https://www.mdpi.com/1420-3049/26/14/4111

Internet

https://www.mdpi.com/1420-3049/26/14/4111

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