Linking Alpha-Synuclein to the Actin Cytoskeleton: Consequences to Neuronal Function

Alpha-Synuclein (αSyn), a protein highly enriched in neurons where it preferentially localizes at the pre-synapse, has been in the spotlight because its intraneuronal aggregation is a central phenomenon in Parkinson’s disease. However, the consequences of αSyn accumulation to neuronal function are n...

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Bibliographic Details
Main Authors: Marina I. Oliveira da Silva, Márcia A. Liz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00787/full