PDGF-D expression is down-regulated by TGFβ in fibroblasts.

PDGF-D expression is down-regulated by TGFβ in fibroblasts.

Transforming growth factor-β (TGFβ) is a key mediator of fibrogenesis. TGFβ is overexpressed and activated in fibrotic diseases, regulates fibroblast differentiation into myofibroblasts and induces extracellular matrix deposition. Platelet-derived growth factor (PDGF) is also a regulator of fibrogen...

Full description

Bibliographic Details
Main Authors: Saima Charni Chaabane, Alexandra Coomans de Brachène, Ahmed Essaghir, Amélie Velghe, Sandra Lo Re, Julie Stockis, Sophie Lucas, Levon M Khachigian, François Huaux, Jean-Baptiste Demoulin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4184810?pdf=render

Internet

http://europepmc.org/articles/PMC4184810?pdf=render

Similar Items